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Research Areas and highlights

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​The Wei Lab works in the highly cross-disciplinary field of BioMEMS, molecular and cellular analysis, and systems biomedicine. We have researchers with diverse expertise ranging from physical sciences, engineering to biology, and we have developed a long-term collaboration with outstanding cancer biologists, clinical oncologists, and the basic and engineering scientists among ISB, UCLA, Caltech, UC Riverside, University of Washington, MIT, and top institutions in China. Wei’s research is supported by several cross-institutional collaborative benchtop-to-bedside programs designated to translate start-of-the-art technologies and concepts into the clinic. These joint efforts allow us to integrate our technologies with systems-level approaches to investigate the cutting-edge cancer biology questions with a balance between discovery and clinical translation.

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Single Cell Multi-Omics Analysis

Microchip-based single cell tools for interrogating the heterogeneous tumor cells and immune cells at multiple biomolecular levels
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Cellular Transition & Epigenetic Plasticity

Resolving the epigenetic regulations, transcriptomic reprogramming, and signaling dynamics associated with adaptive resistance in cancers
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Rare tumor cell analysis in liquid biopsies


​Liquid biopsy-based rare tumor cell analysis for informative cancer diagnostics and immunotherapy.
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