​The Wei Lab works in the highly cross-disciplinary field of BioMEMS, molecular and cellular analysis, and systems biomedicine. We have researchers with diverse expertise ranging from physical sciences, engineering to biology, and we champion cross-disciplinary research approaches and collaborations, which enable us to take on big, complex problems in biomedicine. Our research is supported by several cross-institutional collaborative benchtop-to-bedside programs designated to translate start-of-the-art technologies and concepts into the clinic, including NCI-funded Physical Science in Oncology Network (PS-ON), Cancer Systems Biology Consortium (CSBC), and Innovative Molecular Analysis Technologies (IMAT) Program. These joint efforts allow us to integrate innovative technologies with systems-level computational approaches to investigate the cutting-edge cancer biology questions with a balance between discovery and clinical translation.

---

Single Cell Multi-Omics Analysis
​

Microchip-based single cell multi-omics tools for interrogating the heterogeneous tumor cells and immune cells at multiple biomolecular landscapes

Learn more

Cell State Transition & Epigenetic Plasticity
​

Resolving the transcriptional regulations, epigenetic reprogramming, and signaling network dynamics associated with adaptive cell-state transitions in cancer

Learn More

Spatiotemporal Multi-Omics for
​Tumor-Immune Microenvironment

Spatiotemporal evolution of the tumor immune microenvironment upon clinically relevant drug perturbations​ 

learn more

Rare Cell Analysis for Predictive Cancer Diagnostics & Immunotherapy

​Liquid biopsy-based rare tumor/immune cell analysis for informative cancer diagnostics and immunotherapy
​

learn more